P2Y14R antagonist 4

SKU: orb3028347

Description

Compound 25l, also known as P2Y14R antagonist 4, is an orally active antagonist of the P2Y14R receptor with an IC50 of 5.6 nM. It exhibits higher binding affinity for P2Y14R compared to other PPTN receptors. P2Y14R antagonist 4 also possesses anti-inflammatory properties, reducing the release of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α) induced by LPS.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3081687-67-1
• MW: 532.574
• Formula: C₂₇H₂₇F₃N₂O₄S
• SMILES: O=C(O)C1=CC(=CC(=C1)C2=CC=C(C=C2)C3CCNCC3)NS(=O)(=O)CCC4=CC=C(C=C4)C(F)(F)F
• Target: P2Y Receptor,Interleukin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

P2Y Receptor,Interleukin