P2Y14 antagonist 1

SKU: orb2944365

Description

P2Y14 antagonist 1 (compound 45) is a potent, selective, and orally bioavailable P2Y14 receptor antagonist (IC50 = 0.70 nM). It exhibits anti-inflammatory activity in acute lung injury models by reducing pulmonary immune cell infiltration and suppressing NLRP3 inflammasome signaling, making it a valuable tool for respiratory inflammation research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 399.442
• Formula: C₂₄H₂₁N₃O₃
• SMILES: O=C(OC)C1=CC(C2=NC3=CC=CC=C3N2)=CC(NC(CC4=CC=C(C)C=C4)=O)=C1
• Target: NOD-like Receptor (NLR),P2Y Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455395