P2X4 antagonist-4

SKU: orb2945647

Description

P2X4 antagonist-4 (compound 64) is a selective P2X4 receptor blocker (IC50 = 8 µM) that suppresses ATP-mediated NLRP3 inflammasome activation and IL-1β release. This tool compound is useful for studying neuropathic pain and neuroinflammation in both cellular and animal models of disease.

Research Area

Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

MW	503.545
Formula	C₂₇H₂₂FN₃O₄S
SMILES	CC1=C(C=CC(=C1)F)CS(=O)(=O)NC2=CC=C(C=C2)N3C(=O)CC(=O)NC4=C3C=CC5=CC=CC=C54
Target	P2X Receptor

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

172676843 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols