P162-0948

SKU: orb2944507

Description

P162-0948 is a selective CDK8 inhibitor (IC50: 50.4 nM) that disrupts TGF-β/Smad signaling, reduces EMT protein expression and cell migration in A549 cells, positioning it as a promising research tool for investigating pulmonary fibrosis mechanisms in vitro.

Research Area

Cell Biology

Key Properties

• CAS Number: 1358201-44-1
• MW: 362.357
• Formula: C₂₀H₁₅FN₄O₂
• SMILES: O=C(NCC1=CC=C(F)C=C1)CC2=NN=C(O2)C=3C=CC=4N=CC=CC4C3
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53162184