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Description

This cell-permeable small molecule is a selective inhibitor of Drp1 GTPase activity, which suppresses mitochondrial fission and ROS production. It has demonstrated protective effects on mitochondrial integrity and cell viability in vitro, and reduces fragmentation and oxidative stress in a Parkinson's disease mouse model.

Images & Validation

Key Properties

TargetOthers
CAS Number1411976-18-5
MW2411.80
FormulaC100H179N45O25
SMILESC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CC(C)C)=O)CC(C)C)(=O)N1[C@H](C(N[C@H](C(NCC(N[C@H](C(O)=O)CO)=O)=O)CCCNC(=N)N)=O)CCC1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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