P-gp inhibitor 22

SKU: orb2565545

Description

P-gp Inhibitor 22 is a potent small molecule that blocks P-glycoprotein-mediated drug efflux. This action induces S-phase cell cycle arrest and promotes apoptosis in resistant cell lines like MCF-7/ADR, making it a valuable research tool for studying multidrug resistance in cancer models both in vitro and in vivo.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1226674-74-3
• MW: 348.78
• Formula: C₂₀H₁₃ClN₂O₂
• SMILES: C(#N)C=1C(C2=C3C(=CC=C2OC1N)C=CC(O)=C3)C4=C(Cl)C=CC=C4
• Target: Apoptosis,P-gp

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171391415