P-gp inhibitor 14

SKU: orb2565547

Description

Compound 8a (P-gp inhibitor 14) is a potent, high-affinity P-glycoprotein inhibitor with an EC₅₀ of 48.74 nM, effectively reversing multidrug resistance in vitro. It shows minimal CYP3A4 inhibition and is a valuable research tool for studying drug efflux and chemosensitization in cancer models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2892571-47-8
• MW: 638.71
• Formula: C₃₇H₃₈N₂O₈
• SMILES: O(C)C=1C2=C(C=3C=4C5=C(C(OC)=CC4CN(CC3C1)C6=CC=C(CCN7CC=8C(CC7)=CC(OC)=C(OC)C8)C=C6)OCO5)OCO2
• Target: P-gp

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168432118