p-Aniline-MMAE

SKU: orb2565585

Description

p-Aniline-MMAE is a monomethyl auristatin E (MMAE) derivative conjugated via a para-aniline linker, designed for the synthesis of antibody-drug conjugates (ADCs). This cytotoxic payload is utilized in preclinical research for developing targeted cancer therapies, enabling in vitro and in vivo evaluation of ADC efficacy and mechanism.

Key Properties

• CAS Number: 2748039-81-6
• MW: 867.13
• Formula: C₄₇H₇₄N₆O₉
• SMILES: [C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(N)C=C3)=O)C)[C@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138751687