Oxothiazolidinecarboxylic acid

SKU: orb1301850

Description

Oxothiazolidinecarboxylic acid (Procysteine) serves as a glutathione (GSH) precursor, enhancing cellular antioxidant capacity. It is widely used in research models to study oxidative stress, cytoprotection, and glutathione metabolism in both in vitro and in vivo experimental systems.

Research Area

Metabolism Research

Key Properties

• CAS Number: 19771-63-2
• MW: 147.15
• Purity: 99.97% (May vary between batches)
• Formula: C₄H₅NO₃S
• SMILES: OC(=O)[C@@H]1CSC(=O)N1
• Target: Others,Antioxidant
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (13.59 mM);DMSO:55 mg/mL (373.77 mM)

Bioactivity

• In Vivo:
  Procysteine stimulated gene expression of anabolic factors such as insulin-like growth factor-1, ciliary neurotrophic factor, and cardiotrophin-1. Procysteine supplementation eliminated the aging-associated differences in hepatic GSH and GSH/GSSG ratio. The nSMase activity and ceramide increased in the procysteine-fed mice irrespective of their age. The procysteine-fed aged mice also exhibited hepatic steatosis and triacylglyceride accumulation .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Oxothiazolidine carboxylate, Oxothiazolidinecarboxylic acid, Inhibitor, Antioxidant, Procysteine

Compound Identifiers

PubChem CID

72390