Oxidopamine hydrobromide

SKU: orb1309283

Description

Oxidopamine hydrobromide (6-OHDA HBr) is a dopaminergic neurotoxin that induces inflammation via COX-2/PGE2 upregulation and IL-1β secretion. It is extensively utilized to create in vitro and in vivo Parkinson’s disease models for neurotoxicity and neuroinflammation research.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 636-00-0
• MW: 250.09
• Purity: 99.88% (May vary between batches)
• Formula: C₈H₁₂BrNO₃
• SMILES: Br.NCCc1cc(O)c(O)cc1O
• Target: Dopamine Receptor,Autophagy,Mitophagy
• Solubility: DMSO:125 mg/mL (499.82 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.99 mM);H2O:100 mg/mL (399.86 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Prostaglandin E synthase, PGE synthase, PGE2, p-p38, p38 MAPK, SH-SY5Y cells, 6-Hydroxydopamine, 6-Hydroxydopamine hydrobromide, 6-Hydroxydopamine Hydrobromide, 6-OHDA, 6-OHDA Hydrobromide, 6-OHDA hydrobromide, Autophagy, attention-deficit hyperactivity disorder, Apoptosis, Caspase, COX, Dopamine Receptor, Dopamine, DopamineReceptor, Cyclooxygenase, inhibit, Mitophagy, Mitochondrial Autophagy, PC12 cells, Parkinson's disease, Oxidopamine, Oxidopamine hydrobromide, Oxidopamine Hydrobromide, neurotoxicity, neurotransmitter dopamine, Neuro-2a cells, Interleukin Related, Inhibitor, Lesch-Nyhan syndrome

Compound Identifiers

PubChem CID

176170