OUL232

SKU: orb1744121

Description

OUL232 is a potent and selective small molecule inhibitor targeting PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. It is a valuable chemical probe for investigating mono-ADP-ribosyltransferase function in cancer biology, supporting both in vitro enzymatic assays and in vivo tumor model studies.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 943119-42-4
• MW: 250.28
• Purity: 99.04% (May vary between batches)
• Formula: C₁₀H₁₀N₄O₂S
• SMILES: N=1N=C(N)N2C1SC=3C(OC)=CC=C(OC)C32
• Target: PARP
• Solubility: DMSO:30 mg/mL (119.87 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.99 mM)

Bioactivity

• Target IC50:
  PARP4:11 μM|PARP7:83 nM|PARP10:7.8 nM|TNKS2:10 μM|PARP1:15 μM|PARP12:160 nM|PARP16:3.4 μM|PARP15:56 nM|TNKS1:5.4 μM|PARP2:10 μM|PARP11:240 nM|PARP14:300 nM|PARP3:50 μM
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PARP10, PARP14

Compound Identifiers

PubChem CID

2771058