OTs-C6-OBn

SKU: orb1307325

Description

OTs-C6-OBn is an alkyl chain-based PROTAC linker used in the construction of bifunctional degraders like PROTAC SGK3 degrader-1. This chemical tool is applied in proteolysis-targeting chimera (PROTAC) research for the targeted degradation of proteins in vitro.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 126519-80-0
• MW: 362.48
• Purity: 97.31% (May vary between batches)
• Formula: C₂₀H₂₆O₄S
• SMILES: Cc1ccc(cc1)S(O)(=O)=O.OCCCCCCOCc1ccccc1
• Target: PROTAC Linker
• Solubility: DMSO:Soluble

Bioactivity

• In Vitro:
  PROTACs comprise two distinct ligands linked together, one binding to an E3 ubiquitin ligase and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PROTAC Linkers, PROTACLinker, PROTAC Linker, Inhibitor, inhibit, OTs C6 OBn, OTsC6OBn, OTs-C-6-OBn, OTs-C6-OBn, Alkyl-Chain

Compound Identifiers

PubChem CID

71340451