OSU-53

SKU: orb1738429

Description

OSU-53 is a small molecule activator of AMPK, which consequently inhibits mTOR signaling and stimulates autophagy. It has also been shown to activate pathways in cells with mutations in RAS or BRAF. This compound is used in cancer research, particularly for studying metabolic signaling and oncogenic pathways in both cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 1290069-19-0
• MW: 583.6
• Formula: C₂₅H₂₄F₃N₃O₆S₂
• SMILES: S(NC1=CC=C(/C=C\2/C(=O)N(CC3(C)CCCCC3)C(=O)S2)C=C1)(=O)(=O)C4=CC(C(F)(F)F)=C(N(=O)=O)C=C4
• Target: AMPK,Others,mTOR,ATG,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45378798