OSU-03013

SKU: orb3173890

Description

OSU-03013, an analog of Celecoxib, promotes apoptosis while upregulating E-cadherin and downregulating β-catenin, c-myc, Wnt1, and N-cadherin. It reduces cell migration and invasion capacity and inhibits the proliferation of colon cancer (CC) cells by modulating the expression of Wnt and mTOR. OSU-03013 is utilized in colon cancer research.

Key Properties

• CAS Number: 742112-34-1
• MW: 445.45
• Formula: C₂₅H₁₈F₃N₅
• SMILES: FC(F)(F)C1=NN(C2=CC=C(C=C2)NC(=N)N)C(=C1)C=3C=CC4=C(C=CC=5C=CC=CC54)C3
• Target: Wnt/beta-catenin,c-Myc,mTOR,Cadherin,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Wnt/beta-catenin,c-Myc,mTOR,Cadherin,Apoptosis