Ospemifene

SKU: orb1300609

Description

Ospemifene (FC-1271a) is a selective estrogen receptor modulator (SERM) approved for treating moderate to severe dyspareunia caused by menopausal vulvovaginal atrophy. It is utilized in research on estrogen receptor pharmacology, with studies demonstrating its tissue-selective agonist/antagonist effects in both in vitro and in vivo models.

Research Area

Cell Biology, Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 128607-22-7
• MW: 378.89
• Purity: 99.95% (May vary between batches)
• Formula: C₂₄H₂₃ClO₂
• SMILES: OCCOc1ccc(cc1)C(=C(CCCl)c1ccccc1)c1ccccc1
• Target: Caspase,Estrogen Receptor/ERR,Estrogen/progestogen Receptor
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:55 mg/mL (145.16 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.28 mM);Ethanol:66 mg/mL (174.19 mM)

Bioactivity

• Target IC50:
  ERβ:1633nM|ERα:827nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Ospemifene, EstrogenReceptor, Estrogen Receptor/ERR, Estrogen Receptor, ERR, ER, FC-1271a, Inhibitor, progestogen Receptor, progestogenReceptor

Compound Identifiers

PubChem CID

148127