OSI-296

SKU: orb1699740

Description

OSI-296 is a dual cMET and RON kinase inhibitor with IC50 values of 42 nM and 200 nM, respectively. It demonstrates oral efficacy and tolerability in xenograft models, including bone metastasis, making it a valuable research tool for studying oncogenic signaling pathways in vitro and in vivo.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1175296-94-2
• MW: 465.3
• Formula: C₂₁H₁₉Cl₂FN₄O₃
• SMILES: O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=C3C(C(=CO3)C=4CCN(C(N)=O)CC4)=CN=C2N
• Target: c-Met/HGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44181654