Orvepitant maleate

SKU: orb1706864

Description

Orvepitant maleate is a potent and selective neurokinin-1 (NK-1) receptor antagonist (pKi: 10.2) with good blood-brain barrier penetration. Its research applications include investigations for major depressive disorder and chronic refractory cough, supported by in vitro binding assays and in vivo preclinical studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 579475-24-4
• MW: 744.7
• Formula: C₃₅H₃₉F₇N₄O₆
• SMILES: OC(=O)\C=C/C(O)=O.[H][C@@]12CCC(=O)N1CCN(C2)[C@H]1CCN([C@H](C1)c1ccc(F)cc1C)C(=O)N(C)[C@H](C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
• Target: Neurokinin receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44225656