Ornidazole

SKU: orb1308205

Description

Ornidazole is a nitroimidazole-class antiprotozoal agent effective against amoebic and trichomonal infections. It exhibits partial plasma protein binding and possesses radiosensitizing properties, making it a compound of interest for research in parasitology and in studies investigating combination therapies with radiation.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 16773-42-5
• MW: 219.63
• Purity: 99.91% (May vary between batches)
• Formula: C₇H₁₀ClN₃O₃
• SMILES: CC1=NC=C(N1CC(O)CCl)[N+]([O-])=O
• Target: Antibiotic,Antibacterial,Hedgehog/Smoothened,Parasite
• Solubility: H2O:2 mg/mL (9.11 mM);Ethanol:41 mg/mL (186.68 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.11 mM);DMSO:55 mg/mL (250.42 mM)

Bioactivity

• In Vitro:
  Ornidazole is a 5-nitroimidazole derivative active against protozoa and anaerobic bacteria. It is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Antibiotic, Ornidazole, Ornidazolum, NSC95075, NSC-95075, NSC 95075, Parasite, inhibit, Inhibitor, Tiberal, Ro 7-0207

Compound Identifiers

PubChem CID

28061