ORL1 antagonist 1

SKU: orb1708971

Description

ORL1 antagonist 1 is a potent small molecule inhibitor of the nociceptin/orphanin FQ peptide (NOP) receptor, exhibiting an IC50 of 61 nM. This compound is a valuable pharmacological tool for investigating NOP receptor function in neuropharmacology research, including in vitro binding assays and in vivo behavioral studies related to pain, anxiety, and addiction.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1174985-59-1
• MW: 367.88
• Purity: >99.99% (May vary between batches)
• Formula: C₂₀H₂₂ClN₅
• SMILES: CC1=C(N(N=C1CNC2CCCC2)C3=C(Cl)C=CC=N3)C=4C=CC=NC4
• Target: Opioid Receptor
• Solubility: DMSO:55 mg/mL (149.51 mM)

Bioactivity

• Target IC50:
  ORL1:61 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ORL1 antagonist 1, ORL-1 antagonist 1, Opioid receptor-like1 (ORL1), Opioid Receptor, OpioidReceptor

Compound Identifiers

PubChem CID

44143417