ORL1 antagonist 1

SKU: orb1708971

Description

ORL1 antagonist 1 is a potent small molecule inhibitor of the nociceptin/orphanin FQ peptide (NOP) receptor, exhibiting an IC50 of 61 nM. This compound is a valuable pharmacological tool for investigating NOP receptor function in neuropharmacology research, including in vitro binding assays and in vivo behavioral studies related to pain, anxiety, and addiction.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1174985-59-1
• MW: 367.88
• Purity: >99.99% (May vary between batches)
• Formula: C₂₀H₂₂ClN₅
• SMILES: CC1=C(N(N=C1CNC2CCCC2)C3=C(Cl)C=CC=N3)C=4C=CC=NC4
• Target: Opioid Receptor
• Solubility: DMSO:55 mg/mL (149.51 mM)

Bioactivity

• Target IC50:
  ORL1:61 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ORL1 antagonist 1, ORL-1 antagonist 1, Opioid receptor-like1 (ORL1), Opioid Receptor, OpioidReceptor

Compound Identifiers

PubChem CID

44143417