OR-1896

SKU: orb1708975

Description

OR-1896, the active metabolite of Levosimendan, is a vasodilator and PDE III inhibitor that activates KATP channels. It is a valuable research tool for investigating mechanisms of heart failure and vascular dysfunction in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 220246-81-1
• MW: 245.28
• Purity: 99.51% (May vary between batches)
• Formula: C₁₃H₁₅N₃O₂
• SMILES: C[C@@H]1CC(=O)NN=C1c1ccc(NC(C)=O)cc1
• Target: PDE,Potassium Channel,Drug Metabolite,Apoptosis
• Solubility: DMSO:50 mg/mL (203.85 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.15 mM)

Bioactivity

• In Vitro:
  OR-1896 can achieve vasodilation by activating ATP-sensitive potassium channels in smooth muscle cells.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PDE3, PDE3/PDE Ⅲ, OR 1896, OR1896, OR-1896, Potassium Channel, potassium channel, PotassiumChannel

Compound Identifiers

PubChem CID

9816296