Opiranserin hydrochloride

SKU: orb1297854

Description

Opiranserin hydrochloride is a dual GlyT2 and 5-HT2A receptor antagonist, also inhibiting the P2X3 receptor. It is an investigational injectable agent studied preclinically for its potential to modulate pain pathways, specifically for postoperative pain management.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1440796-75-7
• MW: 430.97
• Purity: 99.33% (May vary between batches)
• Formula: C₂₁H₃₅ClN₂O₅
• SMILES: Cl.CCCCOc1c(OC)cc(cc1OC)C(=O)NCC1(CCOCC1)N(C)C
• Target: 5-HT Receptor,GlyT,P2X Receptor
• Solubility: DMSO:50 mg/mL (116.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.64 mM)

Bioactivity

• Target IC50:
  5-HT2A receptor:1.3 μM|GlyT2:0.86 μM|P2X3 (rat):0.87 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

analgesic, anti-inflammatory, 5-HT Receptor, 5HTReceptor, 5HT Receptor, 5-hydroxytryptamine Receptor, Inhibitor, Glycine transporters, GlyT, GlyT2, inhibit, non-opioid, pain, Opiranserin, Opiranserin hydrochloride, Opiranserin Hydrochloride, P2X Receptor, P2XReceptor, P2XRs, Serotonin Receptor, postoperative, VVZ 149, VVZ149, VVZ-149

Compound Identifiers

PubChem CID

71566777