OPC-14523 dihydrochloride

SKU: orb3177696

Description

OPC-14523 dihydrochloride is the dihydrochloride form of the free base OPC-14523. OPC-14523 dihydrochloride is an orally active dual agonist of sigma receptors and 5-HT₁A receptors that also inhibits the 5-HT transporter, with IC50 values of 47/56 nM for sigma receptors σ1/2, 5-HT₁A receptor IC50 = 2.3 nM, and 5-HT transporter IC50 = 80 nM. OPC-14523 dihydrochloride exhibits antidepressant-like activity. OPC-14523 dihydrochloride can be used in neuroscience research, including studies on antidepressants and neuroprotection.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• MW: 486.86
• Purity: 99.70% (May vary between batches)
• Formula: C₂₃H₃₀Cl₃N₃O₂
• SMILES: COc1c2c(N(C(CC2)=O)CCCN3CCN(c4cc(Cl)ccc4)CC3)ccc1.Cl.Cl
• Target: Sigma receptor,5-HT Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Sigma receptor,5-HT Receptor