OP-3136

SKU: orb3210857

Description

OP-3136 is a selective inhibitor of KAT6. It can reduce the proliferation capability of cancer cells and inhibit cell growth in ER+ breast cancer cell models with KAT6 overexpression. When used in combination with ER antagonists/degraders or CDK4/6 inhibitors, OP-3136 exhibits synergistic anti-tumor activity in mouse xenograft models. It is applicable in research related to HR+/HER2- breast cancer.

Key Properties

• CAS Number: 3056105-63-3
• MW: 462.48
• Formula: C₂₀H₂₂N₄O₇S
• SMILES: O=C(NS(=O)(=O)C=1C(OC)=CC(OC)=CC1OC)C2=NC(OC)=C(C=C2)CN3N=CC=C3
• Target: Histone Acetyltransferase,Estrogen Receptor/ERR,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Histone Acetyltransferase,Estrogen Receptor/ERR,CDK