ONX 0801 trisodium

SKU: orb1691967

Description

ONX 0801 (BGC 945) trisodium is a small molecule inhibitor that selectively targets thymidylate synthase in α-folate receptor-overexpressing tumors. It has demonstrated anti-tumor activity in preclinical in vitro and in vivo models, making it a research tool for investigating targeted cancer therapies.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 1097638-00-0
• MW: 713.58
• Formula: C₃₂H₃₀N₅Na₃O₁₀
• SMILES: [Na].[Na].[Na].OCc1nc(=O)c2cc3[C@H](CCc3cc2[nH]1)N(CC#C)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@H](CCC(O)=O)C(O)=O)C(O)=O
• Target: DNA/RNA Synthesis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137185098