OncoFAP-GlyPro-MMAE

SKU: orb3136588

Description

OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. It is composed of the FAP ligand OncoFAP, a microtubule inhibitor (MMAE), and a linker. OncoFAP-GlyPro-MMAE can be utilized in cancer research, including studies on renal cancer.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2688118-55-8
• MW: 2135.38
• Formula: C₁₀₂H₁₄₁F₂N₁₉O₂₇S
• SMILES: C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(C(NC(CCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CSC4C(=O)N(CCCCCC(NCC(=O)N5[C@H](C(NC6=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N7[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C8=CC=CC=C8)C)=O)C)OC)(CCC7)[H])OC)[C@H](CC)C)C)=O)[C@H](C)C)=O)[C@@H](C)C)C)=O)C=C6)=O)CCC5)=O)C(=O)C4)C(O)=O)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)=O)=CC=C3)N=CC2
• Target: Microtubule Associated,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Microtubule Associated,Others