Omidenepag

SKU: orb1706875

Description

Omidenepag (UR-7276) is a potent and selective EP2 receptor agonist developed as a topical ocular hypotensive agent. It is utilized in glaucoma research, with studies demonstrating its intraocular pressure-lowering efficacy in both in vitro assays and in vivo animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1187451-41-7
• MW: 478.52
• Purity: 99.77% (May vary between batches)
• Formula: C₂₃H₂₂N₆O₄S
• SMILES: OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)n1
• Target: Prostaglandin Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.36 mM);DMSO:100 mg/mL (208.98 mM)

Bioactivity

• Target IC50:
  EP1 (human):10 nM|EP2:1.1 nM （EC50）|EP4 (human):5480 nM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Omidenepag, EP2, h-EP4, h-EP1, Prostaglandin Receptor, ProstaglandinReceptor, UR-7276

Compound Identifiers

PubChem CID

44230575