OMDM-6

SKU: orb1708979

Description

OMDM-6 is a dual-target small molecule acting as an agonist at TRPV1 (EC50 = 75 nM) and CB1 (Ki = 3.2 µM), while also inhibiting anandamide cellular uptake (Ki = 7.0 µM). This profile makes it a useful research tool for investigating endocannabinoid system signaling in both in vitro and in vivo models of pain and neuroinflammation.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 616884-67-4
• MW: 454.64
• Purity: 99.66% (May vary between batches)
• Formula: C₂₈H₄₂N₂O₃
• SMILES: C(NNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)C1=CC(OC)=C(O)C=C1
• Target: TRP/TRPV Channel,Cannabinoid Receptor,Endogenous Metabolite
• Solubility: DMSO:60 mg/mL (131.97 mM)

Bioactivity

• Target IC50:
  Anandamide cellular uptake:Ki: 7.0 μM|TRPV1:75 nM (EC50)|CB1 receptor:Ki: 3.2 μM

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Endogenous Metabolite, anandamide cellular uptake, CB1, Cannabinoid Receptor, CannabinoidReceptor, EndogenousMetabolite, OMDM 6, OMDM6, OMDM-6, TRPChannel, TRP Channel, TRPVChannel, TRPV Channel, TRPV1

Compound Identifiers

PubChem CID

146026185