OM-153

SKU: orb1686533

Description

OM-153 is a potent dual inhibitor of tankyrase 1 and 2 (IC50 = 13 nM and 2 nM, respectively). It suppresses WNT/β-catenin signaling and cellular proliferation, making it a valuable chemical probe for studying Wnt-driven cancers in both in vitro and in vivo research models.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2406278-81-5
• MW: 509.53
• Formula: C₂₈H₂₄FN₇O₂
• SMILES: CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3nccnc23)n1-c1ccccc1F
• Target: PARP,Wnt/beta-catenin,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146282356