Oltipraz

• Catalog Number: orb1310889
• Category: Small Molecules
• Description: Oltipraz
• CAS Number: 64224-21-1
• Purity: 99.56%
• MW: 226.34
• SMILES: CC1=C(SSC1=S)C=2C=NC=CN2
• Formula: C₈H₆N₂S₃
• Biological Activity: Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quinone oxidoreductase 1 (NQO1). The induction of detoxification enzymes enhances the detoxification of certain cancer-causing agents, thereby enhancing their elimination and preventing carcinogen-induced DNA damages. Although the exact mechanism through which the anti-angiogenesis effect remains to be fully elucidated, oltipraz maybe able to modulate the expression of a number of angiogenic factors, thereby blocking the sustained and focal neovascularization in multiple tumor cell types.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.