Olcegepant hydrochloride

SKU: orb1708988

Description

Olcegepant hydrochloride is a potent and selective antagonist of the CGRP1 receptor, exhibiting an IC50 of 0.03 nM and a Ki of 14.4 pM. It is widely used in research to investigate CGRP-mediated pathways in migraine pathophysiology, utilizing both in vitro binding assays and in vivo animal models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 586368-06-1
• MW: 906.11
• Purity: 99.69% (May vary between batches)
• Formula: C₃₈H₄₈Br₂ClN₉O₅
• SMILES: O=C1N(CC=2C(N1)=CC=CC2)C3CCN(C(N[C@H](CC4=CC(Br)=C(O)C(Br)=C4)C(N[C@H](C(=O)N5CCN(CC5)C=6C=CN=CC6)CCCCN)=O)=O)CC3.Cl
• Target: CGRP Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9919272