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OH-Glu-Val-Cit-PAB-MMAE

OH-Glu-Val-Cit-PAB-MMAE

Catalog Number: orb2279070

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Catalog Numberorb2279070
CategorySmall Molecules
DescriptionOH-Glu-Val-Cit-PAB-MMAE is a compound consisting of a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE), used in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number1895916-23-0
Purity98.00%
MW1237.53
SMILES[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(CCCC(O)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
FormulaC63H100N10O15
Biological ActivityOH-Glu-Val-Cit-PAB-MMAE is a compound comprising a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE), utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.