OH-Glu-Val-Cit-PAB-MMAE

SKU: orb2279070

Description

OH-Glu-Val-Cit-PAB-MMAE is a key component for constructing antibody-drug conjugates (ADCs), combining a protease-cleavable linker with the cytotoxic agent MMAE. This construct is widely used in oncology research for developing targeted therapies, with applications in both in vitro cytotoxicity assays and in vivo xenograft studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1895916-23-0
• MW: 1237.53
• Formula: C₆₃H₁₀₀N₁₀O₁₅
• SMILES: [C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(CCCC(O)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132246296