Oditrasertib

SKU: orb1739754

Description

Oditasertib (DNL-788) is a potent and selective RIPK1 inhibitor (IC50 < 100 nM). It is a research tool for investigating RIPK1-driven pathologies, with applications in preclinical studies of neurological and inflammatory diseases, including multiple sclerosis and Alzheimer's disease.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2252271-93-3
• MW: 295.28
• Purity: 99.65%
• Formula: C₁₄H₁₅F₂N₃O₂
• SMILES: N#CC1=CN=CC2=C1OCCN(C(=O)C(C)(C)C(F)F)C2
• Target: RIP kinase
• Solubility: DMSO:80 mg/mL (270.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.18 mM)

Storage & Handling

• Storage: keep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADA 07, ADA-07, DNL-788, Oditrasertib, RIP kinase, RIPK1, RIPkinase

Compound Identifiers

PubChem CID

135382587