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Octyl gallate

SKU: orb1222916

Description

Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. Octyl Gallate has antimetastatic activity. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ug/mL. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. Octyl gallate has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483. (In Vitro):Octyl gallate has antimicrobial activity over H. pylori, with a minimum inhibitory concentration (MIC) value of 125 μg/mL.

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Key Properties

CAS Number1034-01-1
MW282.33
Purity>98% (HPLC)
FormulaC15H22O5
SMILESCCCCCCCCOC(=O)C1=CC(=C(C(=C1)O)O)O
TargetSirtuin
SolubilityDMSO : 125 mg/mL 442.74 mM;

Bioactivity

In Vitro
Octyl gallate has antimicrobial activity over H. pylori, with a minimum inhibitory concentration (MIC) value of 125 μg/mL.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

n-Octyl gallate | Stabilizer GA 8

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Octyl gallate (orb1222916)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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