Ocifisertib hydrochloride

SKU: orb2814658

Description

Ocifisertib hydrochloride is an orally active, potent PLK4 inhibitor (Ki=0.26 nM) that arrests the cell cycle at G2/M and induces apoptosis in cancer cells. It demonstrates robust antitumor efficacy in both cellular assays and mouse xenograft models, supporting its investigation in oncology research.

Research Area

Cell Biology

Key Properties

• CAS Number: 1338799-83-9
• MW: 571.11
• Formula: C₃₃H₃₅ClN₄O₃
• SMILES: O=C1[C@]2([C@@H](C2)C=3C=C4C(=CC3)C(/C=C/C5=CC=C(CN6C[C@@H](C)O[C@@H](C)C6)C=C5)=NN4)C=7C(N1)=CC=C(OC)C7.Cl
• Target: PLK,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

89499466