O6BTG-octylglucoside

SKU: orb1709590

Description

O6BTG-octylglucoside is a potent and cell-permeable MGMT inhibitor, demonstrating high inhibitory activity both in vitro and in cellular assays (IC50 values of 32 nM and 10 nM, respectively). It is a valuable research tool for studying DNA repair mechanisms and for sensitizing cancer cells to alkylating chemotherapeutic agents like temozolomide in experimental models.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 382607-78-5
• MW: 616.53
• Formula: C₂₄H₃₄BrN₅O₇S
• SMILES: [H][C@]1(CO)O[C@@]([H])(OCCCCCCCCn2cnc3c(OCc4cc(Br)cs4)nc(N)nc23)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
• Target: DNA Methyltransferase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10438805