O-Desmethyl Galanthamine

SKU: orb1296966

Description

O-Desmethyl Galanthamine (Sanguinine) is a galanthamine-derived alkaloid that acts as an acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 1.83 μM. This compound is utilized in biochemical research for studying cholinergic neurotransmission and is investigated in models related to cognitive function.

Research Area

Neuroscience

Key Properties

• CAS Number: 60755-80-8
• MW: 273.33
• Purity: 99.62% (May vary between batches)
• Formula: C₁₆H₁₉NO₃
• SMILES: [H][C@]12C[C@@H](O)C=C[C@]11CCN(C)Cc3ccc(O)c(O2)c13
• Target: Cholinesterase (ChE)
• Solubility: DMSO:99 mg/mL (362.2 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.07 mM)

Bioactivity

• Target IC50:
  AChE:1.83 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cholinesterase (ChE), alkaloids, AChE, anti-acetylcholinesterase, inhibit, ODesmethyl Galanthamine, O-Desmethyl Galanthamine, O Desmethyl Galanthamine, Inhibitor, galanthamine-type, Sanguinine

Compound Identifiers

PubChem CID

443722