O-Desmethyl apixaban sulfate sodium

SKU: orb1987467

Description

O-Desmethyl apixaban sulfate sodium is a primary human metabolite of the anticoagulant Apixaban and acts as a direct factor Xa (FXa) inhibitor with a Ki of 58 µM. It is a key reference compound for investigating the pharmacokinetics, metabolism, and anti-thrombotic activity of Apixaban in both in vitro and in vivo research models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 547.52
• Formula: C₂₄H₂₂N₅NaO₇S
• SMILES: O=C(C1=NN(C2=CC=C(OS(=O)(O[Na])=O)C=C2)C3=C1CCN(C4=CC=C(N5C(CCCC5)=O)C=C4)C3=O)N
• Target: Factor Xa

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145925625