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Catalog Number | orb2564731 |
---|---|
Category | Small Molecules |
Description | NVS-STG2 is a STING agonist that promotes the oligomerization of human STING by binding to the pockets between adjacent STING dimer transmembrane domains, effectively acting as molecular glue. It triggers strong STING-mediated immune responses in cells and demonstrates antitumor activity in hSTING knock-in mice. |
Purity | 98.00% |
MW | 427.54 |
CAS Number | [3030588-01-0] |
Formula | C25H33NO5 |
SMILES | O=C(O)C1=CC=C(NCC2=CC=C(C=C2)C3(OCC(C)(C)CO3)C(C)(C)C)C(OC)=C1 |
Storage | -20°C |
Note | For research use only |