NVS-STG2

SKU: orb2564731

Description

NVS-STG2 is a STING agonist that promotes the oligomerization of human STING by binding to the pockets between adjacent STING dimer transmembrane domains, effectively acting as molecular glue. It triggers strong STING-mediated immune responses in cells and demonstrates antitumor activity in hSTING knock-in mice.

Key Properties

• CAS Number: 3030588-01-0
• MW: 427.54
• Formula: C₂₅H₃₃NO₅
• SMILES: O=C(O)C1=CC=C(NCC2=CC=C(C=C2)C3(OCC(C)(C)CO3)C(C)(C)C)C(OC)=C1

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only