NVS-PAK1-C

SKU: orb1694191

Description

NVS-PAK1-1 is a potent, ATP-competitive allosteric inhibitor of PAK1, exhibiting single-digit nM IC50 values against both its phosphorylated and dephosphorylated forms with good selectivity over PAK2. This small molecule is a valuable research tool for studying PAK1 signaling in cancer cell proliferation, invasion, and in vivo tumor models.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2250019-95-3
• MW: 465.9
• Formula: C₂₂H₂₃ClF₃N₅O
• SMILES: C(C(F)F)N1C=2C(C(N[C@@H]3CN(C(N(C)C)=O)CC3)=NC=4C1=CC=C(F)C4)=CC(Cl)=CC2
• Target: Others,PAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

136590564