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Catalog Number | orb1307113 |
---|---|
Category | Small Molecules |
Description | NVP-TAE 226 |
CAS Number | 761437-28-9 |
Purity | 99.17% |
MW | 468.94 |
SMILES | O(C)C=1C=C(C=CC1NC=2N=C(NC3=C(C(NC)=O)C=CC=C3)C(Cl)=CN2)N4CCOCC4 |
Formula | C23H25ClN6O3 |
Biological Activity | NVP-TAE 226 (TAE226) is an effective FAK inhibitor (IC50: 5.5 nM) and most effective to Pyk2(IC50: 3.5 nM); 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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