NVP DPP 728 dihydrochloride

SKU: orb1704992

Description

NVP-DPP728 is a potent and reversible nitrile-based inhibitor of dipeptidyl peptidase IV (DPP-IV) with a Ki of 11 nM. By blocking DPP-IV-mediated GLP-1 degradation, it enhances glucose-stimulated insulin secretion. This inhibitor is a valuable research tool for studying type 2 diabetes mechanisms in both in vitro enzymatic assays and in vivo models.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 247016-69-9
• MW: 298.34
• Formula: C₁₅H₁₈N₆O
• SMILES: C(CNCCNC1=CC=C(C#N)C=N1)(=O)N2[C@H](C#N)CCC2
• Target: DPP-4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9796290