NVP-CLR457

SKU: orb1687227

Description

NVP-CLR457 (compound 40) is an orally bioavailable, balanced pan-class I PI3K inhibitor demonstrating antitumor activity. Its efficacy is supported by a clear dose-dependent pharmacokinetic/pharmacodynamic relationship observed in preclinical studies, making it a useful tool for investigating PI3K signaling in cancer research models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1453082-52-4
• MW: 455.39
• Formula: C₁₈H₂₀F₃N₇O₄
• SMILES: C(O)[C@@H]1N(C(=O)O[C@@H]1C)C=2C=C(N=C(N2)N3CCOCC3)C=4C(C(F)(F)F)=NC(N)=NC4
• Target: Others,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71682837