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Nurr1 agonist 2
Catalog Number: orb1819082
| Catalog Number | orb1819082 |
|---|---|
| Category | Small Molecules |
| Description | Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 μM. Nurr1 agonist 2 can be used to study parkinsonism. |
| Purity | 98.40% |
| MW | 310.37 |
| Biological Activity | Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 μM. Nurr1 agonist 2 can be used to study parkinsonism. |
| CAS Number | 742058-34-0 |
| Formula | C18H14O3S |
| SMILES | C(O)(=O)C=1SC(=CC1)C2=CC=C(OCC3=CC=CC=C3)C=C2 |
| Storage | -20°C |
| Note | For research use only |
LTGO-33 [orb2283849]
97.60%
[2834106-06-6]
467.44
C21H17F4N3O3S
1 mg, 50 mg, 5 mg, 10 mg, 25 mg, 1 ml x 10 mM (in DMSO)
