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NU2058

SKU: orb1304447

Description

NU2058 is a guanine-derived small molecule that functions as a cyclin-dependent kinase (CDK) inhibitor and suppresses DNA topoisomerase II ATPase activity. It is utilized in cancer research for investigating cell cycle arrest and DNA damage mechanisms in both cellular and biochemical assays.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number161058-83-9
MW247.3
Purity98.43% (May vary between batches)
FormulaC12H17N5O
SMILESNc1nc(OCC2CCCCC2)c2nc[nH]c2n1
TargetTopoisomerase,CDK
SolubilityDMSO:60 mg/mL (242.62 mM)

Bioactivity

Target IC50
CDK2:17 μM|CDK2:12 μM (Ki)|CDK1:26 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, guanine-based, O6-(Cyclohexylmethyl)guanine, O(6)-Cyclohexylmethylguanine, NU 2058, NU2058, NU-2058, inhibit, anti-cancer, ATP, Cyclin dependent kinase, CDK1, CDK2, CDK, competitive, Topo II

Similar Products

  • NU-2058 [orb1226060]

    >98% (HPLC)

    161058-83-9

    247.2963

    C12H17N5O

    1 g, 200 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

NU2058 (orb1304447)

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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 80.00
10 mg
$ 80.00
25 mg
$ 130.00
50 mg
$ 150.00
100 mg
$ 210.00
200 mg
$ 290.00
500 mg
$ 440.00
DispatchUsually dispatched within 3-5 working days
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