NTU281

SKU: orb1686793

Description

NTU281 is a potent and selective transglutaminase 2 (TG2) inhibitor. It ameliorates key pathological features of diabetic nephropathy in rodent models, including proteinuria, serum creatinine elevation, glomerular fibrosis, and apoptosis, making it a valuable research tool for studying diabetes-induced glomerulosclerosis.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 815619-12-6
• MW: 487.59
• Formula: C₂₅H₃₁N₂O₆S
• SMILES: [C@H](CC1=CC=CC=C1)(C(N[C@@H](CCC(C[S+](C)C)=O)C(O)=O)=O)NC(OCC2=CC=CC=C2)=O
• Target: Apoptosis,Glutaminase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11433028