NT219

SKU: orb1687933

Description

NT219 is a dual inhibitor of IRS1/2 and STAT3 that promotes misfolded prion protein aggregation and modulates chaperone levels. It is a valuable research tool for studying STAT3 and IRS-driven pathways in cancer and neurodegenerative disease models, both in vitro and in vivo.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1198078-60-2
• MW: 412.26
• Purity: 99.72%
• Formula: C₁₆H₁₄BrNO₅S
• SMILES: Oc1ccc(\C=C\C(=S)NCc2cc(O)c(O)c(O)c2)c(Br)c1O
• Target: STAT,IGF-1R
• Solubility: DMSO:80 mg/mL (194.05 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NT-219, STAT3

Compound Identifiers

PubChem CID

135914977