NSD-IN-3

SKU: orb2565644

Description

NSD-IN-3 is a potent small molecule inhibitor of NSD2 and NSD3 methyltransferases, with IC50 values of 0.81 µM and 0.84 µM, respectively. It reduces H3K36me2 levels, suppresses oncogenic gene expression, and induces S-phase arrest and apoptosis in NSCLC cells, making it a valuable tool for epigenetic and cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Neuroscience

Key Properties

• CAS Number: 744260-15-9
• MW: 334.17
• Formula: C₁₃H₁₂BrN₅O
• SMILES: C(COC1=CC=C(Br)C=C1)N2C=3C(N=C2)=C(N)N=CN3
• Target: Histone Methyltransferase,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

61675786