NSC45586

SKU: orb1298468

Description

NSC45586 is a selective small molecule inhibitor of the protein phosphatases PHLPP1 and PHLPP2. It is a valuable research tool for studying the Akt and PKC signaling pathways in cancer biology, utilized in both cellular and in vivo experimental models.

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 6300-44-3
• MW: 413.4
• Purity: 99.31% (May vary between batches)
• Formula: C₂₀H₁₈N₆NaO₃+
• SMILES: CC1=CC(=C(C=C1N)N)N=NC2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O.[Na+]
• Target: Others
• Solubility: Ethanol:Insoluble;H2O:Insoluble;DMSO:82 mg/mL (198.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PP2C, PHLPP, PHLPP1, PHLPP2, Inhibitor, NSC 45586, inhibit, NSC-45586, NSC45586, pleckstrin homology domain and leucine-rich repeat protein phosphatase, AKT

Compound Identifiers

PubChem CID

135422008