NSC232003

SKU: orb1309318

Description

NSC232003

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1905453-18-0
• MW: 169.14
• Purity: 97.72%
• Formula: C₆H₇N₃O₃
• SMILES: C\C(NO)=C1/C=NC(=O)NC1=O
• Target: E1/E2/E3 Enzyme
• Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble);H2O:2 mg/mL (11.82 mM)

Bioactivity

• In Vitro:
  NSC232003 is an effective DNA methylation inhibitor and indicate that this particular nucleotide scaffold could provide a versatile basis for the design of potent UHRF1 inhibitors.NSC232003, a uracil derivative freely available by the NCI/DTP repository, provides a versatile lead for developing highly potent and cell-permeable UHRF1 inhibitors that will enable dissection of DNA methylation inheritance.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme, UHRF1, E1 activating enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E1Enzyme, E2 Enzyme, E2 conjugating enzyme, E2Enzyme, E3 Enzyme, E3Enzyme, E3 ligating enzyme, Inhibitor, NSC 232003, NSC232003, NSC-232003, inhibit

Compound Identifiers

PubChem CID

314510