NSC109131

SKU: orb1739587

Description

NSC109131 is a potent and selective small molecule inhibitor of the DNA repair enzyme tyrosyl-DNA phosphodiesterase 1 (TDP1). It is a valuable research tool for studying TDP1's role in cellular resistance to topoisomerase I poisons, such as camptothecin, in both in vitro and in vivo cancer research models.

Key Properties

• CAS Number: 21170-27-4
• MW: 478.65
• Formula: C₂₇H₃₄N₄O₂S
• SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@H]2C(CN5C=6C(N=C5)=C(SC)N=CN6)=O)[H]
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

21817802